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Article

Investigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing.

Scientific reports - 27 Sept 2013

Kristensen Lasse Sommer, Treppendahl Marianne Bach, Asmar Fazila, Girkov Mia Seremet, Nielsen Helene Myrtue, Kjeldsen Tina Ellegaard, Ralfkiaer Elisabeth, Hansen Lise Lotte, Grønbæk Kirsten

Abstract excerpt

The tumor suppressor genes MGMT and DAPK1 become methylated in several cancers including diffuse large B-cell lymphoma (DLBCL). However, allelic methylation patterns have not been investigated in DLBCL. We developed a fast and cost-efficient method for the analysis of allelic methylation based on pyrosequencing of methylation specific PCR (MSP) products including a SNP. Allelic methylation patterns were reliably...

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Identifiers

PMID: 24071855
DOI: 10.1038/srep02789
PMCID: PMC3784959

Genes

DAPK1
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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