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Article

Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma.

Oncotarget - 30 Oct 2014

Kristensen Lasse Sommer, Asmar Fazila, Dimopoulos Konstantinos, Nygaard Mette Kathrine, Aslan Derya, Hansen Jakob Werner, Ralfkiaer Elisabeth, Grønbæk Kirsten

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma. Improvements in overall survival have been observed with the introduction of rituximab in combination with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP), however, prognostic markers are still needed. Methylation of the death associated protein kinase (DAPK or DAPK1) gene and TP53 mutations are likely to...

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Share to Antibodies, Monoclonal, Murine-Derived
Share to Apoptosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Death-Associated Protein Kinases

Share to DNA Methylation

Share to Lymphoma, Large B-Cell, Diffuse

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Share to Survival Analysis

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 25229255
DOI: 10.18632/oncotarget.2394
PMCID: PMC4259438

Genes

DAPK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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