Article
Cadherin 6 is a new RUNX2 target in TGF-β signalling pathway.
PloS one - 1 Jan 2013
Sancisi Valentina, Gandolfi Greta, Ragazzi Moira, Nicoli Davide, Tamagnini Ione, Piana Simonetta, Ciarrocchi Alessia
Abstract excerpt
Modifications in adhesion molecules profile may change the way tumor cells interact with the surrounding microenvironment. The Cadherin family is a large group of transmembrane proteins that dictate the specificity of the cellular interactions. The Cadherin switch that takes place during epithelial-mesenchymal transition (EMT) contributes to loosening the rigid organization of epithelial tissues and to enhancing...
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