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Article

Epigenetic regulation of integrin β6 transcription induced by TGF‐β1 in human oral squamous cell carcinoma cells

24 Dec 2017

Abstract excerpt

Overexpression of integrin αvβ6 is believed to play an important role in the invasion and metastasis of oral squamous cell carcinoma (OSCC). However, little is known about the molecular mechanisms leading to αvβ6 upregulation in OSCC. As the integrin β6 (ITGB6) is the only partner with αv, the expression of αvβ6 is dependent on ITGB6, it is, therefore, pivotal to investigate the mechanisms underlying ITGB6...

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PMID: 29274289
DOI: 10.1002/jcb.26642

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