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Article

β-Galactoside α2,6-sialyltranferase 1 promotes transforming growth factor-β-mediated epithelial-mesenchymal transition.

The Journal of biological chemistry - 12 Dec 2014

Lu Jishun, Isaji Tomoya, Im Sanghun, Fukuda Tomohiko, Hashii Noritaka, Takakura Daisuke, Kawasaki Nana, Gu Jianguo

Abstract excerpt

β-Galactoside α2,6-sialyltranferase 1 (ST6GAL1) catalyzes the addition of terminal α2,6-sialylation to N-glycans. Increased expression of ST6GAL1 has been reported in diverse carcinomas and highly correlates with tumor progression. Here, we report that St6gal1 transcription and α2,6-sialylated N-...

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Source

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Identifiers

PMID: 25344606
DOI: 10.1074/jbc.M114.593392
PMCID: PMC4263869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25344606-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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