Article
Prevalence of hepatitis C virus subgenotypes 1a and 1b in Japanese patients: ultra-deep sequencing analysis of HCV NS5B genotype-specific region.
PloS one - 1 Jan 2013
Wu Shuang, Kanda Tatsuo, Nakamoto Shingo, Jiang Xia, Miyamura Tatsuo, Nakatani Sueli M, Ono Suzane Kioko, Takahashi-Nakaguchi Azusa, Gonoi Tohru, Yokosuka Osamu
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) subgenotypes 1a and 1b have different impacts on the treatment response to peginterferon plus ribavirin with direct-acting antivirals (DAAs) against patients infected with HCV genotype 1, as the emergence rates of resistance mutations are different between these two subgenotypes. In Japan, almost all of HCV genotype 1 belongs to subgenotype 1b. METHODS AND FINDINGS: To...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.