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Article

Quantitative imaging in cancer evolution and ecology.

Radiology - 1 Oct 2013

Gatenby Robert A, Grove Olya, Gillies Robert J

Abstract excerpt

Cancer therapy, even when highly targeted, typically fails because of the remarkable capacity of malignant cells to evolve effective adaptations. These evolutionary dynamics are both a cause and a consequence of cancer system heterogeneity at many scales, ranging from genetic properties of individual cells to large-scale imaging features. Tumors of the same organ and cell type can have remarkably diverse...

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Identifiers

PMID: 24062559
DOI: 10.1148/radiol.13122697
PMCID: PMC3781355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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