Article
The biology underlying molecular imaging in oncology: from genome to anatome and back again.
Clinical radiology - 1 Jul 2010
Gillies R J, Anderson A R, Gatenby R A, Morse D L
Abstract excerpt
Cancers are complex, evolving, multiscale ecosystems that are characterized by profound spatial and temporal heterogeneity. The interactions in cancer are non-linear in that small changes in one variable can have large changes on another. These multiple interacting phenotypes and spatial scales can best be understood with appropriate mathematical and computational models. Imaging is central to this investigation...
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