Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Imaging Intratumor Heterogeneity: Role in Therapy Response, Resistance, and Clinical Outcome

24 Nov 2014

Abstract excerpt

Tumors exhibit genomic and phenotypic heterogeneity, which has prognostic significance and may influence response to therapy. Imaging can quantify the spatial variation in architecture and function of individual tumors through quantifying basic biophysical parameters such as CT density or MRI signal relaxation rate; through measurements of blood flow, hypoxia, metabolism, cell death, and other phenotypic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Medical Imaging Techniques and Applications
Share to Radiomics and Machine Learning in Medical Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25421725
DOI: 10.1158/1078-0432.ccr-14-0990

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Imaging Intratumor Heterogeneity: Role in Therapy Response, Resistance, and Clinical OutcomePMID 25421725Read ↗

Mapping Spatiotemporal Heterogeneity in Tumor Profiles by Integrating High-Throughput Imaging and Omics AnalysisSemantic proximity Read ↗

Cancer Metabolism and Tumor Heterogeneity: Imaging Perspectives Using MR Imaging and SpectroscopySemantic proximity Read ↗

Mapping Spatiotemporal Heterogeneity in Tumour Progression by Integrating High-Throughput Imaging and Omics AnalysisSemantic proximity Read ↗

The use of molecular imaging combined with genomic techniques to understand the heterogeneity in cancer metastasis.Semantic proximity Read ↗

Unravelling tumour heterogeneity using next-generation imaging: radiomics, radiogenomics, and habitat imaging.Semantic proximity Read ↗

How clinical imaging can assess cancer biologySemantic proximity Read ↗

Intratumor heterogeneity reflects clinical disease courseSemantic proximity Read ↗

Defining and modeling dynamic spatial heterogeneity within tumor microenvironmentsSemantic proximity Read ↗

Quantitative imaging in cancer evolution and ecology.Semantic proximity Read ↗

Clinical implications of intratumor heterogeneity: challenges and opportunities.Semantic proximity Read ↗

Understanding the Cause and Consequence of Tumor HeterogeneitySemantic proximity Read ↗

Intratumoral Heterogeneity: From Diversity Comes ResistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.