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Article

Rare HRAS alleles and susceptibility to human breast cancer.

Genomics - 1 Jan 1990

Hall J M, Huey B, Morrow J, Newman B, Lee M, Jones E, Carter C, Buehring G C, King M C

Abstract excerpt

The suggestion that inherited rare alleles at the HRAS oncogene locus might be associated with susceptibility to breast cancer led us to test linkage of HRAS and the neighboring region of 11p15 to breast cancer susceptibility in 12 high-risk families. Linkage could be excluded within 17 cM of HRAS; the lod score for close linkage to HRAS was -19.9. In addition, rare HRAS alleles segregated independently of breast...

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Source

Identifiers

PMID: 2406196
DOI: 10.1016/0888-7543(90)90466-8

Genes

HRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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