Article
An allelic variant at the ATM locus is implicated in breast cancer susceptibility.
Genetic testing - 1 Jan 2000
Larson G P, Zhang G, Ding S, Foldenauer K, Udar N, Gatti R A, Neuberg D, Lunetta K L, Ruckdeschel J C, Longmate J, Flanagan S, Krontiris T G
Abstract excerpt
We have tested a simple procedure, disease association by locus stratification, for identifying breast cancer patients with pathogenetic allelic variants at several candidate loci. The strategy was based on the assumption of epistatic interactions of the candidates. We analyzed 66 independent cases from sib pairs affected with breast cancer that had previously been collected during an investigation of...
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