Article
Low-risk susceptibility alleles in 40 human breast cancer cell lines.
BMC cancer - 16 Jul 2009
Riaz Muhammad, Elstrodt Fons, Hollestelle Antoinette, Dehghan Abbas, Klijn Jan Gm, Schutte Mieke
Abstract excerpt
BACKGROUND: Low-risk breast cancer susceptibility alleles or SNPs confer only modest breast cancer risks ranging from just over 1.0 to 1.3 fold. Yet, they are common among most populations and therefore are involved in the development of essentially all breast cancers. The mechanism by which the low-risk SNPs confer breast cancer risks is currently unclear. The breast cancer association consortium BCAC has...
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