Back to search

Article

Modified culture system and combination of FICTION could increase the detection rate of abnormalities in multiple myeloma

2020-06-23

Abstract excerpt

<title>Abstract</title> <p>Background Conventional karyotyping of multiple myeloma (MM) is hampered by the low mitotic index of plasma cells (PCs). Furthermore, low proportions of PCs in some specimens may lead to false negative results in fluorescence <italic>in situ</italic> hybridisation (FISH) detection. The detection rate of cytogenetic abnormalities in MM must therefore be improved. Methods Bone marrow ce...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
42355f94-fc37-5951-b6a5-7eac9aa03c31
DOI
10.21203/rs.3.rs-34934/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 11 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Modified culture system and combination of FICTION could increase the detection rate of abnormalities in multiple myelomaDOI 10.21203/rs.3.rs-34934/v1
Cytogenetic testing by fluorescence in situ hybridization is improved by plasma cell sorting in multiple myelomaSemantic proximity
Imaging flow cytometry-based multiplex FISH for three IGH translocations in multiple myelomaSemantic proximity
A novel human multiple myeloma cell line with genetic abnormality of 1q21 gains only and CKS1B overexpressionSemantic proximity
Phenotype of plasma cells in multiple myeloma and monoclonal gammopathy of undetermined significance.Semantic proximity
Genetic and biological characterization of human myeloma cell lines: An overwiew of the lines established at Kawasaki Medical SchoolSemantic proximity
High-sensitive immunophenotyping and DNA ploidy studies for the investigation of minimal residual disease in multiple myeloma.Semantic proximity
Evidence for ABL amplification in multiple myeloma and therapeutic implicationsSemantic proximity
A novel and easy F xCycle ™ violet based flow cytometric method for simultaneous assessment of DNA ploidy and six‐color immunophenotypingSemantic proximity
A serum-free culture method for myeloma progenitors in vitro: proliferative and immunophenotypic characteristics.Semantic proximity
Development of new adherent mutant from human myeloma-derived cell line: in vitro model of anaplastic transformation of myeloma.Semantic proximity
Primary extramedullary plasmacytoma: similarities with and differences from multiple myeloma revealed by interphase cytogeneticsSemantic proximity
Select a neighboring publication to make it the new centre.