Article
B-cell surface phenotypes of proliferating myeloma cells: target antigens for immunotherapy.
American journal of hematology - 1 Feb 1990
Chan C S, Wormsley S B, Pierce L E, Peter J B, Schechter G P
Abstract excerpt
Dual-parameter flow cytometric analysis of B-cell antigens and DNA content was used to determine the phenotypes of proliferating tumor cells (S-phase cells) from 30 patients with multiple myeloma. B4 (CD19), J5 (CALLA, CD10), B1 (CD20), and monotypic surface immunoglobulin (Slg) were expressed heterogeneously in 24 patients. J5 and monotypic Slg were found most frequently but were always expressed on a...
Topics
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- Cell Division
- Cell Line
- Humans
- Interphase
- Multiple Myeloma
- Phenotype
- Ploidies
