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Article

A variant (rs932335) in the HSD11B1 gene is associated with colorectal cancer in a Chinese population.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Nov 2013

Wang Jirong, Gao Yan, Wang Li, Liu Xinzi, Li Juan, Wang Zhaoxia, Zhou Jianwei, Wang Keming

Abstract excerpt

Glucocorticoid hormones have been reported to contribute to the regulation of cellular proliferation and differentiation and to inhibit the growth of cells in several colon tumors and adenocarcinoma cell lines. As a regulator of glucocorticoid levels, type I isoform HSD11B1 is a bidirectional enzyme but acts predominantly as an oxidoreductase to yield active glucocorticoids, cortisol or corticosterone. To date,...

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PMID: 24061267
DOI: 10.1097/CEJ.0b013e3283656346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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