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Article

NMR structural studies of human cellular prion proteins.

Current topics in medicinal chemistry - 1 Jan 2013

Biljan Ivana, Ilc Gregor, Giachin Gabriele, Legname Giuseppe, Plavec Janez

Abstract excerpt

Prion diseases or transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative disorders associated with the conformational conversion of the cellular prion protein, PrP(C), into a pathological form known as prion or PrP(Sc). They can be classified into sporadic, inherited and infectious forms. Spontaneous generation of PrP(Sc) in inherited forms of prion diseases is caused by mutations in the...

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Identifiers

PMID: 24059340
DOI: 10.2174/15680266113136660169

Genes

GSS
PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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