Article
Genetic comorbidities in Parkinson's disease.
Human molecular genetics - 1 Feb 2014
Nalls Mike A, Saad Mohamad, Noyce Alastair J, Keller Margaux F, Schrag Anette, Bestwick Jonathan P, Traynor Bryan J, Gibbs J Raphael, Hernandez Dena G, Cookson Mark R, Morris Huw R, Williams Nigel, Gasser Thomas, Heutink Peter, Wood Nick, Hardy John, Martinez Maria, Singleton Andrew B
Abstract excerpt
Parkinson's disease (PD) has a number of known genetic risk factors. Clinical and epidemiological studies have suggested the existence of intermediate factors that may be associated with additional risk of PD. We construct genetic risk profiles for additional epidemiological and clinical factors using known genome-wide association studies (GWAS) loci related to these specific phenotypes to estimate genetic...
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