Article
Association of IL-6, TNF-α and IL-10 gene polymorphisms with type 2 diabetes mellitus.
Molecular biology reports - 1 Nov 2013
Saxena Madhukar, Srivastava Neena, Banerjee Monisha
Abstract excerpt
Type 2 diabetes mellitus (T2DM) is a metabolic pro-inflammatory disorder characterized by chronic hyperglycemia and increased levels of circulating cytokines suggesting a causal role of inflammation in its etiology. Polymorphism of cytokine genes including interleukin-6 (IL-6), tumour necrosis factor-α (TNF-α) and interleukin-10 (IL-10) were studied in T2DM patients as well as in normal healthy controls. Genomic...
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