Article
Association of a Large Panel of Cytokine Gene Polymorphisms with Complications and Comorbidities in Type 2 Diabetes Patients.
Journal of diabetes research - 1 Jan 2015
Rodrigues K F, Pietrani N T, Sandrim V C, Vieira C M A F, Fernandes A P, Bosco A A, Gomes K B
Abstract excerpt
AIMS: The polymorphisms of pro- and anti-inflammatory cytokines may be involved in type 2 diabetes (T2D) pathogenesis and its complications. METHODS: We investigated in 102 T2D patients the association of the cytokine polymorphisms in the TNF-α, IL-10, IL-6, TGF-β1, and IFN-γ genes with the T2D microvascular complications and comorbidities (hypertension, dyslipidemia, and obesity). Cytokine genotypes were...
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