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Article

Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants.

Cellular signalling - 1 Jan 2014

Lorenowicz Magdalena J, Macurkova Marie, Harterink Martin, Middelkoop Teije C, de Groot Reinoud, Betist Marco C, Korswagen Hendrik C

Abstract excerpt

Secretion of Wnt proteins is mediated by the Wnt sorting receptor Wls, which transports Wnt from the Golgi to the cell surface for release. To maintain efficient Wnt secretion, Wls is recycled back to the trans-Golgi network (TGN) through a retromer dependent endosome to TGN retrieval pathway. It has recently been shown that this is mediated by an alternative retromer pathway in which the sorting nexin SNX3...

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PMID: 24056045
DOI: 10.1016/j.cellsig.2013.09.013

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SNX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants.PMID 24056045Read ↗

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