Article
Prevalence and genetic analysis of α-thalassemia and β-thalassemia in Chongqing area of China.
Gene - 10 Dec 2013
Yao Xiu-Yun, Yu Jie, Chen Shi-Ping, Xiao Jian-Wen, Zheng Qi-Chen, Liu Hai-Yan, Zhang Lei, Xian Ying, Zou Lin
Abstract excerpt
BACKGROUND AND AIMS: Thalassemia is one of the most common hereditary disorders. This study aimed to investigate the prevalence of thalassemia and the mutation spectrum in Chongqing, the southern area of China. METHODS: A total of 1057 children were recruited from Chongqing. Hematological parameters were examined and globin genes were genetically analyzed. RESULTS: The total frequency of thalassemia carriers was...
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