Molecular Spectrum of α- and β-Thalassemia Mutations in a Large Ethnic Hakka Population in Southern China.

Abstract excerpt

Thalassemia is one of the most prevalent inherited disorders in southern China. However, there have been few reports on molecular characterization of α- and β-thalassemia (α- and β-thal) in the large Hakka population living in Meizhou, a city with high incidence of thalassemia in China. A total of 11,631 in- and outpatients in the Hakka area were analyzed by DNA-based α- and β-thal testing. Of all the samples,...

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