Article
[Prevalence and molecular analysis of β-thalassemia in children of Han ethnicity in Chongqing city].
Zhonghua er ke za zhi = Chinese journal of pediatrics - 1 Jul 2013
Yao Xiu-yun, Zhang Yu-mei, Qin Zhen-zi, Fan Rong, Zou Lin, Chen Shi-ping, Zhang Lei, Xie Qian, Zhong Xiao-yun, Xian Ying, Yu Jie
Abstract excerpt
OBJECTIVE: To investigate the incidence and the gene mutation frequencies and patterns of β-thalassemia (β-Thal) in ethnic Han children in Chongqing city. METHOD: A total of 1726 children were screened by using automatic hemocytic analyzer, cellulose acetate electrophoresis and fetal hemoglobin alkali denaturation test. Samples with mean corpuscular volume (MCV) < 80 fl, cell hemoglobin content (MCH) < 27 pg and...
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