Article
Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities.
Archives of biochemistry and biophysics - 1 Nov 2013
Meneely Kathleen M, Luo Qianyi, Lamb Audrey L
Abstract excerpt
The isochorismate and salicylate synthases are members of the MST family of enzymes. The isochorismate synthases establish an equilibrium for the conversion chorismate to isochorismate and the reverse reaction. The salicylate synthases convert chorismate to salicylate with an isochorismate intermediate; therefore, the salicylate synthases perform isochorismate synthase and isochorismate-pyruvate lyase activities...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
