Article
Polymorphisms in metabolism/antioxidant genes may mediate the effect of dietary intake on pancreatic cancer risk.
Pancreas - 1 Oct 2013
Jansen Rick J, Robinson Dennis P, Stolzenberg-Solomon Rachael Z, Bamlet William R, Tan XiangLin, Cunningham Julie M, Li Ying, Rider David N, Oberg Ann L, Rabe Kari G, Anderson Kristin E, Sinha Rashmi, Petersen Gloria M
Abstract excerpt
OBJECTIVES: A source of variation for inconsistent dietary-pancreatic cancer associations may be individuals carrying constitutional metabolism/antioxidant gene variants that differentially benefit compared to homozygous individuals. Seventy-six tag single-nucleotide polymorphisms were genotyped in 13 candidate genes to test differential associations with pancreatic adenocarcinoma. METHODS: A clinic-based...
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