Article
Body mass index and obesity- and diabetes-associated genotypes and risk for pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2011
Tang Hongwei, Dong Xiaoqun, Hassan Manal, Abbruzzese James L, Li Donghui
Abstract excerpt
BACKGROUND: The genetic factors predisposing individuals with obesity or diabetes to pancreatic cancer have not been identified. AIMS: To investigate the hypothesis that obesity- and diabetes-related genes modify the risk of pancreatic cancer. METHODS: We genotyped 15 single nucleotide polymorphisms of fat mass and obesity-associated (FTO), peroxisome proliferators-activated receptor gamma (PPARγ), nuclear...
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