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Article

Glucose metabolism gene variants modulate the risk of pancreatic cancer.

Cancer prevention research (Philadelphia, Pa.) - 1 May 2011

Dong Xiaoqun, Li Yanan, Chang Ping, Tang Hongwei, Hess Kenneth R, Abbruzzese James L, Li Donghui

Abstract excerpt

Long-term type 2 diabetes is a known risk factor for pancreatic cancer (PC). We hypothesized that genetic variants in glucose metabolism modify individual susceptibility to PC, especially those associated with diabetes. We retrospectively genotyped 26 single-nucleotide polymorphisms of 5 glucose metabolism genes: glucokinase (GCK), glutamine-fructose-6-phosphate transaminase 1 (GFPT1), glucose phosphate isomerase...

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Source

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Identifiers

PMID: 21411499
DOI: 10.1158/1940-6207.CAPR-10-0247
PMCID: PMC3969019

Genes

GCK
GFPT1
GPI
OGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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