Article
Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease.
Drug discovery today. Technologies - 1 Jan 2013
Tardiff Daniel F, Lindquist Susan
Abstract excerpt
Parkinson's disease (PD) is a devastating neurodegenerative disease that affects over one million patients in the US. Yet, no disease modifying drugs exist, only those that temporarily alleviate symptoms. Because of its poorly defined and highly complex disease etiology, it is essential to embrace unbiased and innovative approaches for identifying new chemical entities that target the underlying toxicities...
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