Article
Animal models of Parkinson's disease: limits and relevance to neuroprotection studies.
Movement disorders : official journal of the Movement Disorder Society - 1 Jan 2013
Bezard Erwan, Yue Zhenyu, Kirik Deniz, Spillantini Maria Grazia
Abstract excerpt
Over the last two decades, significant strides has been made toward acquiring a better knowledge of both the etiology and pathogenesis of Parkinson's disease (PD). Experimental models are of paramount importance to obtain greater insights into the pathogenesis of the disease. Thus far, neurotoxin-based animal models have been the most popular tools employed to produce selective neuronal death in both in vitro and...
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