Article
Distribution of selected gene polymorphisms of UGT1A1 in a Saudi population
1 Jan 2013
Abstract excerpt
INTRODUCTION: Glucuronidation is an important phase II pathway responsible for the metabolism of many endogenous substances and drugs to less toxic metabolites, which undergo renal excretion. The aim of the current work was to evaluate genotype and allele frequencies of certain UDP-glucuronosyltransferase 1A1 (UGT1A1) variants in an Arab population. MATERIAL AND METHODS: Genomic DNA was isolated from 192 healthy...
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