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Compound heterozygous UGT1A128 and UGT1A16 or single homozygous UGT1A1*28 are major genotypes associated with Gilbert's syndrome in Chinese Han people.

Gene - 20 May 2021

Zhang Meng, Wang Hongwu, Huang Yuancheng, Xu Xin, Liu Wei, Ning Qin, Chen Tao, Qi Junying

Abstract excerpt

Gilbert's syndrome (GS) is a mild condition characterized by periods of hyperbilirubinemia, which results in variations in the UDP-glucuronosyltransferase 1 (UGT1A1) gene. Variant genotypes of UGT1A1 vary in different populations in the world. The present study aimed to determine the genotype of the UGT1A1 promoter and exon that are related to the serum total bilirubin (STB) level in the Chinese Han population. A...

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Asian People
Bilirubin
China
Gilbert Disease
Glucuronosyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

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PMID: 33631237
DOI: 10.1016/j.gene.2021.145526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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