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Article

ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1.

Nucleic acids research - 1 Dec 2013

Galbraith Matthew D, Saxton Janice, Li Li, Shelton Samuel J, Zhang Hongmei, Espinosa Joaquin M, Shaw Peter E

Abstract excerpt

The ETS domain transcription factor Elk-1 stimulates expression of immediate early genes (IEGs) in response to mitogens. These events require phosphorylation of Elk-1 by extracellular signal-regulated kinase (ERK) and phosphorylation-dependent interaction of Elk-1 with co-activators, including hi...

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Source

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Identifiers

PMID: 24049075
DOI: 10.1093/nar/gkt837
PMCID: PMC3905876

Genes

MED14
CDK8
MED23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24049075-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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