Characterization and prediction of haploinsufficiency using systems-level gene properties in yeast.

Abstract excerpt

Variation in gene copy number can significantly affect organism fitness. When one allele is missing in a diploid, the phenotype can be compromised because of haploinsufficiency. In this work, we identified associations between Saccharomyces cerevisiae gene properties and genome-scale haploinsuffi...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Area Under Curve
• Share to Gene Regulatory Networks
• Share to Genome, Fungal