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Article

The BCL2L10 Leu21Arg variant and risk of therapy-related myeloid neoplasms and de novo myelodysplastic syndromes.

Leukemia & lymphoma - 1 Jul 2014

Fabiani Emiliano, Fianchi Luana, Falconi Giulia, Boncompagni Riccardo, Criscuolo Marianna, Guidi Francesco, La Brocca Antonella, Hohaus Stefan, Leone Giuseppe, Voso Maria Teresa

Abstract excerpt

Therapy-related myeloid neoplasms (t-MNs) are an increasingly recognized complication in patients previously treated with radiotherapy and/or chemotherapy for cancer or autoimmune disease. Single nucleotide variants (SNVs) in genes involved in the cellular pathways of detoxification, DNA repair and apoptosis may modify the individual risk of developing a t-MN. We studied the frequency of the SNVs of six genes...

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Source

Identifiers

PMID: 24047476
DOI: 10.3109/10428194.2013.845885

Genes

GSTA1
GSTM1
GSTP1
GSTT1
NQO1
RAD51
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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