Article
Effect of donor KIR2DL1 allelic polymorphism on the outcome of pediatric allogeneic hematopoietic stem-cell transplantation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Oct 2013
Bari Rafijul, Rujkijyanont Piya, Sullivan Erin, Kang Guolian, Turner Victoria, Gan Kwan, Leung Wing
Abstract excerpt
PURPOSE: Killer-cell immunoglobulin-like receptors (KIRs) that regulate natural-killer cells are highly polymorphic. Some KIR2DL1 alleles encode receptors that have stronger signaling function than others. We tested the hypothesis that the clinical outcomes of allogeneic hematopoietic stem-cell transplantation (HSCT) could be affected by donor KIR2DL1 polymorphism. PATIENTS AND METHODS: All 313 pediatric patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
