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Article

Insight into the structural stability of wild type and mutants of the tobacco etch virus protease with molecular dynamics simulations.

Journal of molecular modeling - 1 Nov 2013

Wang Yu, Zhu Guo-Fei, Ren Si-Yan, Han Yong-Guang, Luo Yue, Du Lin-Fang

Abstract excerpt

The efficiency and high specificity of tobacco etch virus protease (TEVp) has made it widely used for cleavage of recombinant fusion proteins. However, TEVp suffers from a few intrinsic defects such as self-cleavage, poorly expressed in E. coli and less soluble. So some mutants were designed to i...

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Identifiers

PMID: 24043540
DOI: 10.1007/s00894-013-1930-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24043540-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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