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Article

Enhancing the stability and solubility of TEV protease using in silico design.

Protein science : a publication of the Protein Society - 1 Nov 2007

Cabrita Lisa D, Gilis Dimitri, Robertson Amy L, Dehouck Yves, Rooman Marianne, Bottomley Stephen P

Abstract excerpt

The ability to rationally increase the stability and solubility of recombinant proteins has long been a goal of biotechnology and has significant implications for biomedical research. Poorly soluble enzymes, for example, result in the need for larger reaction volumes, longer incubation times, and more restricted reaction conditions, all of which increase the cost and have a negative impact on the feasibility of...

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Identifiers

PMID: 17905838
DOI: 10.1110/ps.072822507
PMCID: PMC2211701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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