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Article

Functional analysis of HIV-1 Vpr: identification of determinants essential for subcellular localization.

Virology - 1 Oct 1995

Mahalingam S, Collman R G, Patel M, Monken C E, Srinivasan A

Abstract excerpt

Vpr is a conserved HIV-1 auxiliary protein that localizes to the nuclear region of cells. Vpr is also present in virions, and it is directed into the assembling virus when coexpressed with Gag. Each of these two localization activities may be important for Vpr function, and we recently identified regions of Vpr that are critical for virion incorporation. In this study we analyzed the Vpr domains involved in...

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PMID: 7571402
DOI: 10.1006/viro.1995.1490

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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