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Article

Functional analysis of HIV-1 Vpr: identification of determinants essential for subcellular localization.

Virology - 1 Oct 1995

Mahalingam S, Collman R G, Patel M, Monken C E, Srinivasan A

Abstract excerpt

Vpr is a conserved HIV-1 auxiliary protein that localizes to the nuclear region of cells. Vpr is also present in virions, and it is directed into the assembling virus when coexpressed with Gag. Each of these two localization activities may be important for Vpr function, and we recently identified...

Topics

Amino Acid Sequence
Amino Acids
Cell Nucleus
Conserved Sequence
Gene Products, vpr
HIV-1
HeLa Cells
Humans
Molecular Sequence Data
Mutation
Protein Structure, Secondary
vpr Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7571402
DOI: 10.1006/viro.1995.1490

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7571402-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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