Article
Sensitivity of a ribavirin resistant mutant of hepatitis C virus to other antiviral drugs.
PloS one - 1 Jan 2013
Mihalik Kathleen B, Feigelstock Dino A
Abstract excerpt
BACKGROUND: While ribavirin mono-therapy regimens have minimal effect on patients with chronic hepatitis C virus (HCV) infections, they can be efficacious when combined with interferon. Clinical studies show that interferon-free combination therapies containing ribavirin are also efficacious, suggesting that an interferon-free therapy could be adopted in the near future. However, generation of drug resistant...
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