Genetic risk scores based on risk-associated single nucleotide polymorphisms can reveal inherited risk of bladder cancer in Chinese population.

doi:10.1097/MD.0000000000019980

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Genetic risk scores based on risk-associated single nucleotide polymorphisms can reveal inherited risk of bladder cancer in Chinese population.

Medicine - 1 May 2020

Xu Chenyang, Lin Xiaoling, Qian Wei, Na Rong, Yu Hongjie, Jia Haifei, Jiang Haowen, Fang Zujun, Zheng S Lilly, Ding Qiang, Wu Yishuo, Zheng Jie, Xu Jianfeng

Abstract excerpt

Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) associated with bladder cancer (BCa) risk in Caucasian and East Asian population. The objective of this study was to validate these SNPs in Chinese population and evaluate whether these SNPs could differentiate the individual inherited risk for BCa.A case-control study including 581 BCa cases and 1561 healthy controls was...

Topics

Aged
Asian People
Case-Control Studies
China
Female
Gene Frequency
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microtubule-Associated Proteins

Middle Aged

Odds Ratio

Polymorphism, Single Nucleotide

Receptor, Fibroblast Growth Factor, Type 3

Risk Assessment

Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 32384449
DOI: 10.1097/MD.0000000000019980
PMCID: PMC7220229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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