Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ACB-PCR measurement of spontaneous and furan-induced H-ras codon 61 CAA to CTA and CAA to AAA mutation in B6C3F1 mouse liver.

Environmental and molecular mutagenesis - 1 Oct 2013

Banda Malathi, Recio Leslie, Parsons Barbara L

Abstract excerpt

Furan is a rodent liver carcinogen, but the mode of action for furan hepatocarcinogenicity is unclear. H-ras codon 61 mutations have been detected in spontaneous liver tumors of B6C3F1 mice, and the fraction of liver tumors carrying H-ras codon 61 CAA to AAA mutation increased in furan-treated mice. Allele-specific competitive blocker PCR (ACB-PCR) has been used previously to quantify early, carcinogen-induced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon
Share to Furans
Share to Gene Amplification

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, ras

Share to Liver Neoplasms

Share to Mutagens

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 24038307
DOI: 10.1002/em.21808

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ACB-PCR measurement of spontaneous and furan-induced H-ras codon 61 CAA to CTA and CAA to AAA mutation in B6C3F1 mouse liver.PMID 24038307Read ↗

Levels of 4-aminobiphenyl-induced somatic H-ras mutation in mouse liver DNA correlate with potential for liver tumor development.Semantic proximity Read ↗

ACB-PCR measurement of K-ras codon 12 mutant fractions in livers of Big Blue rats treated with N-hydroxy-2-acetylaminofluorene.Semantic proximity Read ↗

Aristolochic acid-induced carcinogenesis examined by ACB-PCR quantification of H-Ras and K-Ras mutant fraction.Semantic proximity Read ↗

Detection of a mouse H-ras codon 61 mutation using a modified allele-specific competitive blocker PCR genotypic selection method.Semantic proximity Read ↗

Spontaneous mutation at codon 61 of the Ha-ras gene in the nascent liver of B6C3F1, C3H/He and C57BL/6 mice.Semantic proximity Read ↗

Mutagenicity of furan in female Big Blue B6C3F1 mice.Semantic proximity Read ↗

Transgenic models for detection of mutations in tumors and normal tissues of rodents.Semantic proximity Read ↗

H- and K-ras mutational profiles in chemically induced liver tumors from B6C3F1 and CD-1 mice.Semantic proximity Read ↗

Ras mutations in methylclofenapate-induced B6C3F1 and C57BL/10J mouse liver tumours.Semantic proximity Read ↗

Temporal changes in the mutant frequency and mutation spectra of the 61st codon of the H-ras oncogene following exposure of B6C3F1 mice to N-nitrosodiethylamine (DEN).Semantic proximity Read ↗

Dose-related changes in the profile of ras mutations in chemically induced CD-1 mouse liver tumors.Semantic proximity Read ↗

Accumulation of K-Ras codon 12 mutations in the F344 rat distal colon following azoxymethane exposure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.