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Article

Polymorphisms in the HIV-1 gp41 env gene, natural resistance to enfuvirtide (T-20) and pol resistance among pregnant Brazilian women.

Journal of medical virology - 1 Jan 2014

Reis Mônica Nogueira da Guarda, de Alcântara Keila Correa, Cardoso Ludimila Paula Vaz, Stefani Mariane Martins Araújo

Abstract excerpt

The selective pressure of antiretroviral drugs (ARVs) targeting HIV-1 pol can promote drug resistance mutations in other genomic regions, such as env. Drug resistance among women should be monitored to avoid horizontal and mother-to-child transmission. To describe natural resistance to T-20 (enfuvirtide), gp41 env polymorphisms, mutations in pol and HIV-1 subtypes, 124 pregnant women were recruited. For 98...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

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Share to HIV Envelope Protein gp41

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Share to pol Gene Products, Human Immunodeficiency Virus

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Source

Identifiers

PMID: 24037943
DOI: 10.1002/jmv.23738

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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