Article
HIV-1 primary and secondary antiretroviral drug resistance and genetic diversity among pregnant women from central Brazil.
Journal of medical virology - 1 Mar 2010
Cardoso Ludimila Paula Vaz, Pereira Gisner Alves Souza, Viegas Angela Alves, Schmaltz Luiza Emylce Pelá Rosado, Stefani Mariane Martins de Araújo
Abstract excerpt
Antiretroviral (ARV) resistance mutations in HIV-1 may reduce the efficacy of prophylactic therapy to mother-to-child transmission and impact future treatment options. ARV resistance mutations and HIV-1 phylogenetic diversity in protease (PR) and reverse transcriptase (RT) genes were assessed among 77 pregnant women (35 naïve, 42 treated with ARV) from Goiânia/Goiás, central west Brazil. ARV mutations in PR/RT...
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