Article
Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues.
AIDS research and human retroviruses - 1 Aug 2012
Jones Leandro R, Moretti Franco, Calvo Andrea Y, Dilernia Darío A, Manrique Julieta M, Gómez-Carrillo Manuel, Salomón Horacio
Abstract excerpt
We studied drug resistance mutations (DRMs) in 2623 pol sequences. Out of 94,828 amino acid substitutions that were detected, 8749 corresponded to nucleoside reverse transcriptase inhibitor (NRTI), 3765 to nonnucleoside reverse transcriptase inhibitor (NNRTI), and 7141 to protease inhibitor (PI) resistance-associated mutations. The most common DRMs were L10I, I54V, L90M, V82A, A71V, L10V, M46I, M184V, M41L,...
Topics
- Adolescent
- Adult
- Amino Acid Sequence
- Anti-Retroviral Agents
- Argentina
- Child
- Child, Preschool
- Drug Resistance, Viral
- Female
- Gender Identity
- HIV
- HIV Infections
- Humans
- Infant