Article
Short telomeres are frequent in hereditary breast tumors and are associated with high tumor grade.
Breast cancer research and treatment - 1 Sept 2013
Martinez-Delgado Beatriz, Gallardo Mercedes, Tanic Miljana, Yanowsky Kira, Inglada-Perez Lucia, Barroso Alicia, Rodriguez-Pinilla Maria, Cañamero Marta, Blasco Maria A, Benitez Javier
Abstract excerpt
Telomere shortening is a common event involved in malignant transformation. Critically short telomeres may trigger chromosomal aberrations and produce genomic instability leading to cancer development. Therefore, telomere shortening is a frequent molecular alteration in early stages of many epith...
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