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Telomere‐mediated genomic instability and the clinico‐pathological parameters in breast cancer

21 Aug 2008

Abstract excerpt

A study was undertaken to correlate telomere dysfunction and genomic instability with the histopathological grades and the estrogen and progesterone receptor status in breast cancer. Sixty-one archived breast tissues (38 cancer tissues and 23 paired normal tissues) were used in the study. The breast tumor tissues showed significantly shorter telomeres (7.7 kb) compared with the paired adjacent tissues (9.0 kb) by...

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Share to Cancer Cells and Metastasis
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PMID: 18720522
DOI: 10.1002/gcc.20608

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