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Article

Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases.

Journal of medical genetics - 1 May 2012

Martinez-Delgado Beatriz, Yanowsky Kira, Inglada-Perez Lucia, de la Hoya Miguel, Caldes Trinidad, Vega Ana, Blanco Ana, Martin Teresa, Gonzalez-Sarmiento Rogelio, Blasco Maria, Robledo Mercedes, Urioste Miguel, Song Honglin, Pharoah Paul, Benitez Javier

Abstract excerpt

BACKGROUND: Alterations in telomere maintenance mechanisms leading to short telomeres underlie different genetic disorders of ageing and cancer predisposition syndromes. It is known that short telomeres and subsequent genomic instability contribute to malignant transformation, and it is therefore likely that people with shorter telomeres are at higher risk for different types of cancer. Recently, the authors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22493152
DOI: 10.1136/jmedgenet-2012-100807

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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