Article
Shorter telomeres and high telomerase activity correlate with a highly aggressive phenotype in breast cancer cell lines.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2016
Ceja-Rangel Hugo A, Sánchez-Suárez Patricia, Castellanos-Juárez Emilio, Peñaroja-Flores Rubicelia, Arenas-Aranda Diego J, Gariglio Patricio, Benítez-Bribiesca Luis
Abstract excerpt
Maintenance of telomere length is one function of human telomerase that is crucial for the survival of cancer cells and cancer progression. Both telomeres and telomerase have been proposed as possible biomarkers of cancer risk and cancer invasiveness; however, their clinical relevance is still under discussion. In order to improve our understanding of the relationship between telomere length and telomerase...
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