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Article

Disruption of mitotic arrest precedes precocious differentiation and transdifferentiation of pregranulosa cells in the perinatal Wnt4 mutant ovary.

Developmental biology - 15 Nov 2013

Maatouk Danielle M, Mork Lindsey, Chassot Anne-Amandine, Chaboissier Marie-Christine, Capel Blanche

Abstract excerpt

Mammalian sex determination is controlled by antagonistic pathways that are initially co-expressed in the bipotential gonad and subsequently become male- or female-specific. In XY gonads, testis development is initiated by upregulation of Sox9 by SRY in pre-Sertoli cells. Disruption of either gen...

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Source

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Identifiers

PMID: 24036309
DOI: 10.1016/j.ydbio.2013.08.026
PMCID: PMC4066978

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24036309-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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