Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation of the Theiler's virus leader protein zinc-finger domain impairs apoptotic activity in murine macrophages.

Virus research - 6 Nov 2013

Son Kyung-No, Liang Zhiguo, Lipton Howard L

Abstract excerpt

The Theiler's murine encephalomyelitis virus (TMEV) leader (L) protein zinc-finger domain was mutated to study its role in cell death in infection of the murine macrophage cell line M1-D, revealing that an intact zinc-finger domain is required for full apoptotic activity. A functional L zinc-fing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to bcl-2-Associated X Protein
Share to Macrophages

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Structure, Tertiary

Share to Rodent Diseases

Share to Theilovirus

Share to Tumor Suppressor Protein p53

Share to Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24036175
DOI: 10.1016/j.virusres.2013.09.001
PMCID: PMC4267530

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-24036175-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Mutation of the Theiler's virus leader protein zinc-finger domain impairs apoptotic activity in murine macrophages.PMID 24036175Read ↗

A protein critical for a Theiler's virus-induced immune system-mediated demyelinating disease has a cell type-specific antiapoptotic effect and a key role in virus persistence.Semantic proximity Read ↗

Cloning and characterization of a novel RING-B-box-coiled-coil protein with apoptotic function.Semantic proximity Read ↗

A Novel CCCH-Zinc Finger Protein Family Regulates Proinflammatory Activation of MacrophagesSemantic proximity Read ↗

Induction of apoptosis by the c-Myc helix-loop-helix/leucine zipper domain in mouse 3T3-L1 fibroblasts.Semantic proximity Read ↗

Apoptotic cells, including macrophages, are prominent in Theiler's virus-induced inflammatory, demyelinating lesions.Semantic proximity Read ↗

Ubiquitin-independent degradation of antiapoptotic MCL-1.Semantic proximity Read ↗

Anthrax lethal factor proteolysis and inactivation of MAPK kinase.Semantic proximity Read ↗

Z-DNA-binding protein 1-mediated programmed cell death: Mechanisms and therapeutic implicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.